Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Molecular Weight (g/mol)
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3,316
R&D Systems™ CHC
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. MCT inhibitor; decreases glycoloysis
3,317
R&D Systems™ RIPGBM
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant
| Target | RIP Kinase Inhibitors |
|---|---|
| CAS | 355406-76-7 |
| Purity | 98% |
| Chemical Name or Material | N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H21FN2O3 |
3,318
R&D Systems™ MRS 2211
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A Tocris product, part of R&D Systems. Competitive P2Y13 antagonist
| Solubility | Soluble to 70mM in water |
|---|---|
| Chemical Name or Material | 2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde disodium salt |
| Recommended Storage | Desiccate at -20°C |
| Molecular Formula | C14H10N4O8Na2PCl |
| Formula Weight | Observed MW: 474.66 |
| Assay Percent Range | >96% |
3,319
R&D Systems™ TM 5275 sodium salt
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Plasminogen activator inhibitor-1 (PAI-1) inhibitor; orally bioavailable
| Target | Additional Synthetic Protease Inhibitors |
|---|---|
| CAS | 1103926-82-4 |
| Purity | >98% |
| Chemical Name or Material | 5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C28H27ClN3NaO5 |
| Formula Weight | 543.97 |
3,320
R&D Systems™ NKY 80
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 299442-43-6 Molecular Formula: C12H11N3O2
| CAS | 299442-43-6 |
|---|---|
| Molecular Formula | C12H11N3O2 |
3,321
R&D Systems™ Spermine tetrahydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 306-67-2 Molecular Formula: C10H30Cl4N4
| CAS | 306-67-2 |
|---|---|
| Molecular Formula | C10H30Cl4N4 |
3,322
R&D Systems™ Progesterone
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 57-83-0 Molecular Formula: C21H30O2
| CAS | 57-83-0 |
|---|---|
| Molecular Formula | C21H30O2 |
3,323
R&D Systems™ SJ 1008030
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective JAK2 Degrader (PROTAC™)
3,324
R&D Systems™ Linifanib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R
| Target | PDGF R beta |
|---|---|
| CAS | 796967-16-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-[4-(3-Amino-1 H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H18FN5O |
3,325
R&D Systems™ Pomalidomide 4'-PEG2-acid
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Cereblon ligand with PEG linker and terminal acid for onward chemistry
3,326
R&D Systems™ W146
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective S1P1 receptor antagonist
3,327
R&D Systems™ ANA 12
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 219766-25-3 Molecular Formula: C22H21N3O3S
| CAS | 219766-25-3 |
|---|---|
| Molecular Formula | C22H21N3O3S |
3,328
R&D Systems™ Calhex 231 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 652973-93-8 Molecular Formula: C25H27ClN2O
| CAS | 652973-93-8 |
|---|---|
| Molecular Formula | C25H27ClN2O |
3,329
R&D Systems™ Hoechst 33342
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 875756-97-1 Molecular Formula: C27H31Cl3N6O
| CAS | 875756-97-1 |
|---|---|
| Molecular Formula | C27H31Cl3N6O |
3,330
R&D Systems™ TP 238
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. CECR2 and BPTF/FALZ inhibitor